EMBRYONIC POLARITY AND THE SOMA-GERMLINE DICHOTOMY

Our lab studies the earliest stages of embryogenesis to understand how single-celled eggs develop into complex multicellular embryos. We focus on the choice between soma and germline, one of the first developmental decisions faced by embryos. Our goal is to identify and characterize the molecular mechanisms that polarize embryos and distinguish between somatic and germline cells. We use the nematode Caenorhabditis elegans (C. elegans) as a model system and have recently developed scalable methods for precision genome engineering in this animal.

 

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