Publications

  1. Paix, A, Rasoloson, D, Folkmann, A, Seydoux, G. Rapid Tagging of Human Proteins with Fluorescent Reporters by Genome Engineering using Double-Stranded DNA Donors. Curr Protoc Mol Biol. 2019;129 (1):e102. doi: 10.1002/cpmb.102. PubMed PMID:31710422 .
  2. Ouyang, JPT, Folkmann, A, Bernard, L, Lee, CY, Seroussi, U, Charlesworth, AG et al.. P Granules Protect RNA Interference Genes from Silencing by piRNAs. Dev. Cell. 2019;50 (6):716-728.e6. doi: 10.1016/j.devcel.2019.07.026. PubMed PMID:31402283 PubMed Central PMC6764750.
  3. Cable, J, Brangwynne, C, Seydoux, G, Cowburn, D, Pappu, RV, Castañeda, CA et al.. Phase separation in biology and disease-a symposium report. Ann. N. Y. Acad. Sci. 2019;1452 (1):3-11. doi: 10.1111/nyas.14126. PubMed PMID:31199001 PubMed Central PMC6751006.
  4. Putnam, A, Cassani, M, Smith, J, Seydoux, G. A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos. Nat. Struct. Mol. Biol. 2019;26 (3):220-226. doi: 10.1038/s41594-019-0193-2. PubMed PMID:30833787 PubMed Central PMC6668929.
  5. Folkmann, AW, Seydoux, G. Spatial regulation of the polarity kinase PAR-1 by parallel inhibitory mechanisms. Development. 2019;146 (6):. doi: 10.1242/dev.171116. PubMed PMID:30814118 PubMed Central PMC6451319.
  6. Lee, CY, Seydoux, G. Dynamics of mRNA entry into stress granules. Nat. Cell Biol. 2019;21 (2):116-117. doi: 10.1038/s41556-019-0278-5. PubMed PMID:30664788 PubMed Central PMC6779317.
  7. Forman-Kay, JD, Kriwacki, RW, Seydoux, G. Phase Separation in Biology and Disease. J. Mol. Biol. 2018;430 (23):4603-4606. doi: 10.1016/j.jmb.2018.09.006. PubMed PMID:30213727 PubMed Central PMC6779308.
  8. Folkmann, AW, Seydoux, G. Single-molecule study reveals the frenetic lives of proteins in gradients. Proc. Natl. Acad. Sci. U.S.A. 2018;115 (38):9336-9338. doi: 10.1073/pnas.1812248115. PubMed PMID:30181287 PubMed Central PMC6156616.
  9. Seydoux, G. The P Granules of C. elegans: A Genetic Model for the Study of RNA-Protein Condensates. J. Mol. Biol. 2018;430 (23):4702-4710. doi: 10.1016/j.jmb.2018.08.007. PubMed PMID:30096346 PubMed Central PMC6779309.
  10. Paix, A, Folkmann, A, Goldman, DH, Kulaga, H, Grzelak, MJ, Rasoloson, D et al.. Precision genome editing using synthesis-dependent repair of Cas9-induced DNA breaks. Proc. Natl. Acad. Sci. U.S.A. 2017;114 (50):E10745-E10754. doi: 10.1073/pnas.1711979114. PubMed PMID:29183983 PubMed Central PMC5740635.
  11. Lee, CS, Lu, T, Seydoux, G. Nanos promotes epigenetic reprograming of the germline by down-regulation of the THAP transcription factor LIN-15B. Elife. 2017;6 :. doi: 10.7554/eLife.30201. PubMed PMID:29111977 PubMed Central PMC5734877.
  12. Greider, C, Hopkins, N, Steitz, J, Amon, A, Asai, D, Barres, B et al.. Not just Salk. Science. 2017;357 (6356):1105-1106. doi: 10.1126/science.aao6221. PubMed PMID:28912235 .
  13. Mok, CA, Au, V, Thompson, OA, Edgley, ML, Gevirtzman, L, Yochem, J et al.. MIP-MAP: High-Throughput Mapping of Caenorhabditis elegans Temperature-Sensitive Mutants via Molecular Inversion Probes. Genetics. 2017;207 (2):447-463. doi: 10.1534/genetics.117.300179. PubMed PMID:28827289 PubMed Central PMC5629315.
  14. Paix, A, Folkmann, A, Seydoux, G. Precision genome editing using CRISPR-Cas9 and linear repair templates in C. elegans. Methods. 2017;121-122 :86-93. doi: 10.1016/j.ymeth.2017.03.023. PubMed PMID:28392263 PubMed Central PMC6788293.
  15. Smith, J, Calidas, D, Schmidt, H, Lu, T, Rasoloson, D, Seydoux, G et al.. Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3. Elife. 2016;5 :. doi: 10.7554/eLife.21337. PubMed PMID:27914198 PubMed Central PMC5262379.
  16. Housden, BE, Muhar, M, Gemberling, M, Gersbach, CA, Stainier, DY, Seydoux, G et al.. Loss-of-function genetic tools for animal models: cross-species and cross-platform differences. Nat. Rev. Genet. 2017;18 (1):24-40. doi: 10.1038/nrg.2016.118. PubMed PMID:27795562 PubMed Central PMC5206767.
  17. Paix, A, Schmidt, H, Seydoux, G. Cas9-assisted recombineering in C. elegans: genome editing using in vivo assembly of linear DNAs. Nucleic Acids Res. 2016;44 (15):e128. doi: 10.1093/nar/gkw502. PubMed PMID:27257074 PubMed Central PMC5009740.
  18. Paix, A, Folkmann, A, Rasoloson, D, Seydoux, G. High Efficiency, Homology-Directed Genome Editing in Caenorhabditis elegans Using CRISPR-Cas9 Ribonucleoprotein Complexes. Genetics. 2015;201 (1):47-54. doi: 10.1534/genetics.115.179382. PubMed PMID:26187122 PubMed Central PMC4566275.
  19. Wang, JT, Smith, J, Chen, BC, Schmidt, H, Rasoloson, D, Paix, A et al.. Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans. Elife. 2014;3 :e04591. doi: 10.7554/eLife.04591. PubMed PMID:25535836 PubMed Central PMC4296509.
  20. Chen, BC, Legant, WR, Wang, K, Shao, L, Milkie, DE, Davidson, MW et al.. Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution. Science. 2014;346 (6208):1257998. doi: 10.1126/science.1257998. PubMed PMID:25342811 PubMed Central PMC4336192.
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